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However, their dysregulation can exacerbate inflammation and tissue damage in ARDS ( Given the central role of oxidative stress and lipid peroxidation in ARDS, targeting ferroptosis represents a promising therapeutic strategy ( 2 Ferroptosis in infection and ARDS development Cell death pathways play critical roles in immune homeostasis, infection defense, and inflammation resolution
A compound with limited human data, an unresolved safety history, and no approval isby definitionnot a validated therapy
In rare case instances blood pressure may drop
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A similar application may be prevention of Ab-mediated rejection of organ transplants, which occurs when the human leukocyte antigen profiles of the donor and recipient do not match [361]
