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An important player in podocytes physiology is the protein nephrin, a podocyte-specific protein, which is responsible for the maintenance of the integrity of the filtration barrier

It carries about one quarter of vitamin B12 in serum Transcobalamin I (haptocorrin) and III bind inactive or circulating B12 pools 2 More about the transcobalamins: TCB I and III: 6070kDa molecular weight proteins Belong to the haptocorrin (HC) superfamily HCs, also called R-binders or cobalophilins, are found in various tissues and biological fluids TCB I and III are derived from the granulocyte line and are markers of neutrophilic secondary granules, which explains their increase in myeloproliferative disorders (MPDs)

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5 The distinct mechanism of the MpRALF1MpFERMpLLG complex assembly