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Frontiers in Pharmacology, 12, 2021

Red flags that require medical evaluation See your healthcare provider if dry mouth is severe enough to interfere with eating, speaking, or sleeping despite implementing management strategies

Most gastrointestinal side effects of tirzepatide, including nausea and diarrhea, are most severe during the first few weeks of treatment or after dose increases and typically diminish within several days to weeks as the body adapts to the medication

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