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Moreover, the methylation-specific multiplex ligation-dependent probe amplification analysis currently represents the test of choice for confirming the diagnosis of PWS in almost 99% of cases [2]

FIGURE 2 Then, due to the important role of MCK1/GSK3 in cell signaling, we focused our attention on this genetic repressor of CYS4 -OE induced phenotypes

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The trial met its primary endpoint, demonstrating statistically significant and superior weight loss with CagriSema versus placebo