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Together, these data demonstrate that FN-mediated MEK/ERK activation counteracts MITF nuclear accumulation and melanin synthesis, suggesting that MEK/ERKpotentially downstream of FAK act as negative regulators of melanogenesis in response to ECM cues

Carnitine is synthesized in the liver, but also can be obtained through the diet

Li H, Wang J, Wu C, Wang L, Chen ZS, Cui W

Advances in metabolic research have positioned glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as a promising therapeutic option for MASH, extending their use beyond diabetes and obesity management

doi: 10.1016/j.ejphar.2018.01.037 54 MatthysPHatseSVermeireKWuytsABridgerGHensonGWet al