Some laboratory investigations have reported involvement of pathways linked to MAPK/ERK signaling and transcriptional regulatory networks, which are commonly associated with cellular proliferation and differentiation processes in vitro[2]
The angle depends on available tissuewith more tissue, you can inject more steeply (90 degrees), with less tissue, more shallowly (45 degrees)
Since there have been some interesting developments in both the diagnosis and treatment of B12 deficiency, and since B12 deficiency remains so common, this seems like a good opportunity for some updates
NAD + -regulated genome stability and gene transcription in carcinogenesis NAD + metabolism is not only essential for metabolic and redox homeostasis, but also required for epigenetic reprogramming in tumorigenesis
The scientific literature is presently woefully short of research in this area
And if you're dealing with thinning hair and haven't had much luck with minoxidil or finasteride, it's tempting to take all of that at face value
