Brestoff JR, Giwa R, Jia W, Field RL
10.1016/S0887-8994(97)00026-X Matsumoto J, Ogawa H, Maeyama R, Okudaira K, Shinka T, Kuhara T, Matsumoto I: Successful treatment by direct hemop-erfusion of coma possibly resulting from mitochondrial dysfunction in acute valproate intoxication
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It promotes insulin release when blood sugars are high, minimizes glucagon levels to control glucose production, and slows gastric emptying to aid in prolonged satiety and reduced calorie intake
PubMed Jafek, B
Patients in major clinical trials have tolerated these combinations without unexpected adverse events beyond the known side effect profiles of each drug individually