The species studied included Sprague-Dawley rats, CD-1 mice, Beagle dogs, and cynomologus monkeys treated with-naphthoflavone or phenobarbital (all species), isoniazid (rat), pyrasole (monkey), dexamethasone (rat, mouse, monkey), rifampin (dog), or clofibric acid (rat, mouse, dog)
Patients and providers stress that abrupt discontinuation reverses hard-won progress in weight loss and health, risking a resurgence of diabetes, hypertension, sleep apnea, joint pain, and cardiovascular disease
Injection site reactions are typical of any subcutaneous peptide
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Proactive dietary modifications can help counteract these changes and support weight maintenance without the pharmacological assistance previously provided
Food and Drug Administration, FDA Adverse Event Reporting System (FAERS) Database, Accessed 2 November 2024
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