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The maximum plasma concentrations (C(max)) of adducts for immediate release (IR) and extended release (ER) formulations were 0.108 (0.020) and 0.100 (0.028) nmol/mL serum, respectively, and were two orders of magnitude lower than the maximum APAP adduct levels previously reported in adults with acute liver failure secondary to APAP

In contrast to the hydrophobic ligands, the support matrix should be inert to minimize undesired and unpredictable interactions with sample molecules

and 3) HFD mixed with 0.01% -tocopherol (-tocopherol group)

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