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PaoliPPDonleyDStablerDSaseendranathANicolsonSWSimpsonSJet al

doi: 10.1038/sj.ijo.0801083 Summary Keywords Prader-Willi syndrome, obesity, GLP-1 receptor agonist, semaglutide, metabolic surgery Citation Koceva A, Mleku Kozamernik K, Jane A, Herman R, Ferjan S and Jensterle M (2025) Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review

GLP-1RAs reduce glycemia in patients with T2DM by increasing glucose-induced insulin secretion and inhibiting glucagon secretion via the stimulation of pancreatic GLP1 receptors in beta and alpha cells and by increasing insulin sensitivity [5]

Brand GLP-1 at $1,000+/month eventually approaches surgery cost