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The samples were then vortexed and dried down using a nitrogen evaporator

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It also targets other cells in the pancreas to stop the glucagon signal for generating glucose in the liver.[ref] In clinical trials, GLP-1 RAs improved lipid profiles, increased satiety, slowed gastric emptying, reduced inflammation, and had neuroprotective effects.[ref] The slowing of gastric emptying and reducing inflammation may play a role in weight loss, along with the decrease in appetite and eating less

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The KEGG analysis revealed the activation of pathways associated with adaptive metabolism and circadian regulation, encompassing circadian rhythm, starch and sucrose metabolism, arginine and proline metabolism, lipolysis regulation in adipocytes, and HIF-1 signaling (Figure 6d)