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Stimulation of these receptors by GLP-1RAs may lead to cellular overgrowth, hyperplasia, chronic low-grade, or acute inflammation

[Rapid weight loss through GLP-1 receptor agonists as lifestyle phenomenon and implications for plastic esthetic medicine]

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This mechanism couples with an increased endothelial expression of adhesion molecules [64, 65] and both intersect with a dysregulated pro-inflammatory cascade