In comparison, a multicenter clinical trial on IGB use reported a total body weight loss of 8.5% at 3 months, 11.8% at 6 months, and 13.3% at 12 months, while semaglutide studies have shown approximately 10.9% weight loss at 6 months and 13.9% at 12 months [12, 13]
One item worth noting for informed decision-making: a March 2026 STAT News analysis reported that at least 30 percent of the telehealth companies that received FDA warning letters for compounded GLP-1 marketing violations shared clinical affiliations with one of four nationwide medical groups - and OpenLoop was named as one of those four
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doi: 10.1038/s41598-017-02838-2 32