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Notably, patients who exhibited significant increases in the autophagy marker LC3-II in PBMCs showed better survival outcomes, suggesting that stronger autophagy inhibition may provide greater benefit [99, 102]
It is an injectable treatment that uses a purified form of the botulinum toxin to temporarily paralyze muscles, resulting in a smoother and more youthful appearance
TongTTongTYNApplebyPNArmstrongMEGFensomGKKnuppelAet al
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This mechanism has been validated among lung cancer patients from four distinct geographic regions, suggesting that PM2.5 exposure may trigger lung cancer-related gene mutations through APOBEC3B and DDR (DNA damage response) pathway activation [151]
Ferreira et al., 2021)
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