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The pioneering 2017 Phase 1b trial of setmelanotide (mentioned above), while providing a critical proof-of-concept for weight loss in a small cohort of heterozygous carriers, was primarily designed as an exploratory study

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Chemical optimization of selective Pseudomonas aeruginosa LasB elastase inhibitors and their impact on LasB-Mediated activation of IL-1 in cellular and animal infection models

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