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**** Thyroid function disturbances **** Potential for kidney dysfunction , leading even to kidney failure Severe abdominal pain Incorrect technique of injection (especially by an untrained person) can result in sepsis, HIV, & other infections Conclusions There is no published data for either the safety or efficacy of glutathione injections for skin lightening.There is very little evidence that establishes either the safety or efficacy of glutathione injections for skin lightening