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Nature medicine 2016;22, 7883, doi: Schoenwaelder, S

Enhances serotonin production, improving mood

By working through the nasal mucosa, the therapy provides rapid absorption and a more direct route to the bloodstream than oral options

Rat studies show interesting effects: accelerated tendon and ligament healing, gut lining repair, reduced inflammation across multiple tissue types, and improved muscle recovery

10f-THF: 10-formyltetrahydrofolate 5mTHF: 5-methyltetrahydrofolate AICAR: P-ribosyl-5-amino-4-imidazole carboxamide CH = THF: 5-10-methenyltetrahydrofolate CH2-THF: 5-10-methylenetetrahydrofolate Cys: cysteine Cysta cystathionine DHF: dihydrofolate DMG: dimethylglycine dTMP: deoxythymidine monophosphate dUMP: deoxyuridine monophophate GAR: glycinamide ribonucleotide Glut: glutamate Glut: Cys glutamyl-cysteine Gly: glycine