At the molecular levels, HSCs express the genes which encode for enzymes such as matrix metalloproteinase (MMP)-1 (interstitial collagenase) (Casini et al., 1994), which digests native fibrillar collagen types I and III, and MMP-2 (Milani et al., 1994), which digests denatured collagen types I and III and native collagen type IV, as well as tissue inhibitors of MMPs (TIMP)-1 and TIMP-2 (Iredale et al., 1992)
However, as with any bioactive compound, some risks and precautions apply
[DOI] [PubMed] [Google Scholar] 69.Richards P, Parker HE, Adriaenssens AE, et al
For long-term studies, it is highly recommended to aliquot the stock solution into single-use volumes in sterile microcentrifuge tubes and store them frozen at -20C or -80C
The right approach depends on your symptoms, your history, and your goals
Unlike Ozempic and Wegovy, which contain semaglutide, Mounjaro activates both GLP-1 and GIP pathways