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Moving Forward With Semaglutide Constipation Semaglutide constipation is a well-recognized side effect tied to how these medications slow digestion, and for most people it responds to simple changes in hydration, fiber, and activity

These habits prevent the most common quality-of-life issues in older GLP-1 patients

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14,16 In the brain, GLP-1RAs bind to receptors in the hypothalamus to promote satiety and reduce food intake