The relative fluorescence units (RFU) from each sample were normalized based on (1) hybridization controls on each microarray to correct for systematic variability in hybridization and (2) median signal based on all features for each dilution to correct for variability across plates according to the SomaScan Data Standardization guidelines (SomaScan Data Standardization and File Specification Technical Note (SSM-020))
Increased circulating IL-8 is associated with reduced IGF-1 and related to poor metabolic control in adolescents with type 1 diabetes mellitus
These mimic a hormone, normally found in the small intestine, that plays a key role in appetite control and digestion
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Baseline demographics by age group show that 24% were aged 45-54, 38% aged 55-64, 30% aged 65-74 and 8% aged 75 years plus