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Most patients report reduced hunger signals, less intense food cravings, and a quicker sense of fullness during meals within 3 to 7 days of starting therapy

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Headache, back pain, arthralgia, diarrhea, vomiting, and pyrexia are typical adverse effects

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95% CI, 6.968.46), suggesting that unhealthy dietary patterns may further increase the likelihood of progression from UC to cholangiocarcinoma through pathways such as chronic inflammation (Nie and Zhao, 2017)