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A rather simple but very effective method of removing dominant epitopes to enhance responses to conserved subdominant epitopes involved the removal of the S1 portion of spike containing the RBD and then the administration of a vaccine with only S2 as a DNA vaccine or protein [73] (Table 2)

1035 Although lecanemab and donanemab are for individuals with MCI due to Alzheimer's disease or mild dementia due to Alzheimer's disease, the actual number of people who may be eligible to receive the treatments is projected to be much smaller due to strict eligibility criteria

In 2024, this market had about $15 billion in sales