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But Kessler had recently begun taking a GLP-1 agonist: an anti-obesity medication that suppresses food cravings by mimicking the effects of a gut hormone called glucagon-like peptide-1

We advise a at least 6 months of treatment for this protocol

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So the BMI that counts towards eligibility is the BMI at the time of GLP-1 initiation, not necessarily the patients current BMI