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Glutathione decreases oxidative stress, and that protects cells from this damage

Elevated H3K27ac levels were observed in the striatum of humans and rats using heroin, highlighting its importance in opioid dependence

Additionally, one study indicated that HMGB1 can upregulate heme oxygenase 2 and transferrin expression through the RAS-JNK/p38 pathway, promoting erastin-induced ferroptosis [101]

Erratum in: CNS Drugs

Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells

GSH Induced Controlled Release of Levofloxacin from a Purpose-Built Prodrug: Luminescence Response for Probing the Drug Release in Escherichia coli and Staphylococcus aureus