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HGF influenced the metastasis of c-MET-positive cells into multiple organs, including the liver, kidney, lymph nodes, lung, gonads, and the central nervous system, in SCID mice but did not affect metastasis of c-MET-negative lymphoma [15]

Pathway bias analysis using parameters derived from this cellular model again further supports that, relative to liraglutide, PF-06882961 has minor (3-fold) bias away from internalization (vs

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