The mechanism likely stems from biomechanical shifts and inadequate core adaptation rather than direct drug toxicity
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This has not been studied, but it is theoretically possible
These links reflect shared immunogenetic factors, including IL-18, IFN-, CTLA-4, HLA-DQ8, HLA-DQ2, HLA-B8, and HLA-DR3, many of which are integral to antigen presentation within the major histocompatibility complex (MHC)
Given the colocalization of PAR2 within the enteroendocrine populations, we hypothesized that protease-specific PAR2 signaling in the gut might modulate postprandial incretin secretion
Transient receptor potential vanilloid cation channel subtype (TRPV1) and transient receptor potential ankyrin (TRPA1) play a crucial role in visceral sensation and pain [208]