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IMS, ER lumen, peroxisome, plasma-membrane microdomains, nucleus) and (3) embed specificity controlsSOD (for O 2 ), catalase/GPx mimetics (for H 2 O 2 ), metal chelators like DFO/TPEN (to suppress Fenton chemistry) and pathway inhibitors or genetic ablations (e.g., NOX isoform blockers, mitochondrial site inhibitors, siRNA/CRISPR) (Murphy et al

Future research directions are also discussed to advance our understanding and treatment of free radical-associated diseases

Ferritinophagy-mediated Ferroptosis Is Involved in Sepsis-Induced Cardiac Injury

The side effect profiles of these medications reflect their distinct mechanisms of action and help guide patient selection

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