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Combination Approaches Combining glutaminase inhibitors with standard therapies may boost effectiveness

DPP-4 carries out its exopeptidase activity by cleaving proteins or peptides after encountering a proline or alanine in the second position from the N-terminal end of the amino acid chain

Patients and physicians have reported severe gastrointestinal complications involving persistent vomiting, severe nausea, abdominal pain, dehydration, malnutrition, and delayed stomach emptying that, in some cases, required hospitalization or emergency room treatment

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doi:10.1093/hmg/11.3.331

Variation in HLA class I genes, particularly certain HLA-B alleles, has been associated with differences in how effectively the body controls HSV-2 shedding and recurrence