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10.1007/s11033-022-07673-x 88 MeiB.LiH.ZhuJ.YangJ.YangZ.WenZ.et al (2017)
Data show that, among patients with more advanced hepatic fibrosis (i.e., F3-F4 stages), older age, obesity, thrombocytopenia, and higher GGT activity (transformed in log scale) were independent correlates of the risk for liver-related events (defined as ascites, variceal hemorrhage, encephalopathy, jaundice, or hepatocellular carcinoma) [54]
Maintenance Therapy : For ongoing maintenance, a monthly injection of 1 mg (1000 g) is generally sufficient to maintain adequate vitamin B12 levels in most adults
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To create a model devoid of resident macrophages without impeding the recruitment of circulating macrophages, the researchers administered clodronate liposome earlier, at 8 days before cryoinjury
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