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In such conditions, the APX-MDHAR system could work largely as a closed cycle, with minimal or minor input from glutathione (Fig

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3.2 Transmembrane proteins and CHAC1 3.2.1 Notch Notch is a highly conserved transmembrane protein crucial for regulating cell fate decisions, differentiation, proliferation, and apoptosis during development and in adult tissues

These organelles lacked cristae and had high levels of ROS

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