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The copper peptide research overview covers the full mechanism and the ~4,000 human genes documented as GHK-Cu-responsive in Broad Institute Connectivity Map analysis

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The proposed mechanism centers on modulation of the nitric oxide system: BPC-157 counteracts L-NAME-induced eNOS blockade in rat models and supports vascular sprouting through VEGFR2 internalization (Hsieh et al., J Mol Med , 2017)

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