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It has been suggested that this process is an important mechanism in sensing and signaling redox disturbances such as increased ROS production [138,143]

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MTHFR impairment affects longevity not through a single pathway but through at least five distinct biological mechanisms, each contributing to a different dimension of accelerated biological aging

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PDE4 and Epac1 synergistically promote rectal carcinoma via the cAMP pathway