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Other studies have shown that many people regain weight after stopping the drugs, including one published in December from Novo Nordisk competitor Eli Lilly: People using the GLP-1 drug Zepbound, which uses the active ingredient tirzepatide and targets a second hormone called GIP, lost an average of 21% of their body weight over 36 weeks

The first day I took it I felt energized- Ive started walking again

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Because Medicare Part D is currently not permitted to cover GLP-1s for weight loss, it appears that the Centers for Medicare & Medicaid Services (CMS) will create a pilot program to cover the drugs beginning as early as April 2026