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While the analogy isn't perfect, it captures the essence of why researchers often prefer localized protocols for joint-specific studies
Additionally, lactate metabolism enhances cellular NADPH availability through a glucose-sparing mechanism: When cells use lactate as their primary fuel source, glucose is redirected towards the PPP, which generates NADPH essential for fatty acid biosynthesis (28)
Failure of glial cell-line derived neurotrophic factor (GDNF) in clinical trials orchestrated by reduced NR4A2 (NURR1) transcription factor in Parkinson's disease
E.PurnellJ
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