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The study began with the stimulation of murine bone marrow-derived macrophages (BMDMs) with TLR ligands under conditions of carbon starvation which comprised no glucose, pyruvate or glutamine

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Semaglutide is FDA-approved under different brand names: Ozempic and Rybelsus for type 2 diabetes

oxidative stress, calcium, and glutamate toxicity overload may also lead to energy deficiencies, forming a vicious cycle with -synuclein accumulation