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In a clinical trial, people with type 2 diabetes who took tirzepatide experienced a reduction in body weight of approximately 16 to 28 pounds after one year of treatment (Ludvik, 2021)

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Tirzepatide proved that dual incretin agonism produces superior outcomes to GLP-1 agonism alone in the SURPASS-2 head-to-head trial against semaglutide

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