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In one systematic review, 544 papers were screened, 36 met the inclusion criteria, and 35 of those were in rodents or cells
M., Goldberg, G
In nonclinical mouse studies, animals with genetic melanocortin pathway defects were more responsive to setmelanotide than wild-type mice (79, 81)
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This can cause dry, itchy, sensitive skin, and worsening of pre-existing conditions such as eczema and dermatitis
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