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Lower Overall Treatment Cost Cost remains a major concern for many patients

For evidence-based weight loss, prescription GLP-1 medications and structured lifestyle support remain the most reliable routes

GLP-1 receptors in the mesolimbic system are implicated in the modulation of reward behavior [134], while brain imaging studies document GLP-1-induced changes in brain regions related to appetite and reward, such as the insula, amygdala, putamen, and orbitofrontal cortex [135]

An update for this topic was in progress during this manuscript's development [94]

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The authors acknowledged certain study limitations and emphasized that these findings underscore the need for patient-centered nutritional guidance, potentially involving Registered Dietitian Nutritionists, to optimize health outcomes and address identified dietary education gaps