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It is this dual action that explains why tirzepatides efficacy data consistently surpasses that of its predecessors

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After 72 weeks, people taking the highest tolerated dose of Zepbound had lost an average of 20.2% of their starting weight

Past studies looking at the safety of the thymosin alpha-1 peptide found the most common side effects were local irritation, discomfort, or redness at the injection site

Safety data for GLP-1 receptor agonists now spans nearly two decades of clinical use, beginning with exenatide in 2005 and expanding through semaglutide trials that enrolled tens of thousands of participants