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After 4 weeks at the new tirzepatide dose, evaluate and titrate up or down based on weight trend and tolerability

[DOI] [PMC free article] [PubMed] [Google Scholar] 305

Week-by-week titration schedules built around the 10 mg supply

Clinical trials highlight their ability to promote significant weight loss, improve metabolic markers, and enhance quality of life for patients across various demographics

Individuals with a history of medullary thyroid carcinoma (a rare neuroendocrine tumor known as MTC) or multiple endocrine neoplasia syndrome type 2 (a hereditary cancer known as MEN 2) should not take semaglutide due to an increased risk of thyroid C-cell tumors in rodents

doi: 10.1111/dom.12605 222 KristensenSLRrthRJhundPSDochertyKFSattarNPreissDet al