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Similarly, ROS produced in normal physical processes play an important role in the maintenance of cell function, but excessive ROS may cause metabolic disorders, such as lipid peroxidation, and induce ferroptosis [74, 75]

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Short-acting formulations reach peak plasma concentrations within 1-3.5 hours and have shorter elimination half-lives, while long-acting agents like semaglutide have half-lives of approximately one week, allowing for sustained therapeutic effects

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