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In: Morgan & Mikhail's Clinical Anesthesiology, 6e
The plenary session on treatment and harm reduction measures explored new and proven interventions from heroin-assisted treatment and long-acting buprenorphine to mobile and app-based overdose prevention tools, with insights from Alexei Lakhov (EuroNPUD) on user perspectives and digital harm reduction
The ATTAIN-2 results reinforce the potential for orforglipron, as a once-daily oral, to deliver meaningful weight loss and A1C reduction, consistent with similar landmark trials for injectable GLP-1s, Custer added
But combinations require careful medical supervision to improve dosing and monitor for interactions
This solution contains bacteriostatic agents to support multi-use applications under appropriate laboratory conditions
This step might involve acid-base catalysis by the active-site cysteinyl thiolate (which could explain an effect of the second cysteinyl residue), and/or the conserved lysine residue, yielding GS in analogy to glutathione transferases (Fig
