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Some additional benefits of liver support include a reduction of fatigue, brain fog, anxiety, and depression, as well as clearer skin, improved vitamin and mineral absorption, and better bowel function

Copper associates with differential methylation in placentae from two US birth cohorts

PMID 15662293

In rat models

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[108] In addition, certain drugs may interfere with laboratory tests for the vitamin, such as amoxicillin, erythromycin, methotrexate and pyrimethamine