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The reason the who should avoid list is framed so broadly is not boilerplate caution

Peripherally, these agents induce significant weight loss, enhance insulin sensitivity, and reduce hepatic de novo lipogenesis

The standard dosing regimen begins with 3 mg once daily for one month, increasing to 7 mg daily, with a possible further increase to 14 mg daily if additional glycaemic control is needed

One group of studies, called the STEP trials , focused on people who were overweight or obese but did not have diabetes

Individuals need to consult with their healthcare provider and consider all the possible side effects before starting any treatment

Diabetes, obesity & metabolism, 23(9), 20582066