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Computer modeling of the binding of AR antagonists such as flutamide, nilutamide and bicalutamide also suggested that both polar and hydrophobic interactions are essential for proper binding to anchor those compounds into the pocket 192

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Jennis M, Kung CP, Basu S, Budina-Kolomets A, Leu JI, Khaku S, et al

Effect of androgens on plasma somatomedin-C/insulin-like growth factor I responses to growth hormone

Ross SA, Brown JC, Dupr J