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Our findings indicate that FOXO4-DRI promotes apoptosis in senescent cells by disrupting the FOXO4-P53 interaction, thereby releasing and phosphorylating P53, which then translocates to the cytoplasm

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Supernatants were transferred to clean sample plates, diluted with 0.55 M metoprolol in water and were analysed by LC-MS/MS for amine metabolites

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