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10.21037/jtd.2019.12.64 4

Accessed 5/31/2019

If you've lost less than 5%, options include: Titrating to a higher Zepbound dose Adding a second medication (e.g., metformin, topiramate) Switching to a different GLP-1 or GLP-1/GIP medication Reassessing diet, exercise, and behavioral factors Most patients who switch from Wegovy to Zepbound and titrate to at least 7.5 mg reach the 5% threshold by week 16