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Related peptides in the GLP-1 agonist class with broader receptor profiles include retatrutide (a GLP-1/GIP/glucagon triple agonist) and tirzepatide (a GLP-1/GIP dual agonist)

Conjugation of GSH with electrophilic compounds is mainly mediated by the glutathione- S -transferases (GSTs), a super family of Phase II detoxification enzymes

10.1016/j.neulet.2009.02.020 Neurosci

doi: 10.1002/med.21712 27

JJ: Conceptualization, Writingoriginal draft, Writingreview & editing, Funding acquisition

Current treatment modalities include the off-label use of common drugs such as N-acetylcysteine and metronidazole to lower the production and promote detoxification of toxic H2S