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Hydrophobic ion pairing (HIP) of (poly)peptide drugs: benefits and drawbacks of different preparation methods

Alterations in mitochondrial dynamics [4], reactive oxygen species production [5], mitophagy [6], and mitochondrial-related gene expression, such as that of mitochondrial transcription factor A ( Tfa m) and uncoupling protein 2 (Ucp2) [7, 8], may underlie mitochondrial-induced -cell failure

Lee W-H, Loo C-Y, Young PM, Traini D, Mason RS, Rohanizadeh R

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Safety profile of acarbose, an alpha-glucosidase inhibitor