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From Figure 1 of Mehta et al

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Neuroprotection & Cognitive Enhancement Research reveals significant brain penetration capabilities with enhanced synaptic transmission producing 40% increases in excitatory post-synaptic potential

More notably, substantial CD8 + T-cell infiltration and aberrant PD-L1 signaling have been observed in AD brain tissues, suggesting the presence of a locally immunosuppressive microenvironment

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The gene therapy is delivered using a minimally invasive endoscopic infusion directly into the pancreas, which is guided by ultrasound